Metabolomics And Its Role in Inflammatory Bowel Disease-What Do We Know?
نویسندگان
چکیده
Inflammatory bowel diseases comprise of ulcerative colitis and Crohn’s disease, both which have increasing incidence. Despite not having completely understood pathogenesis, genetic factors, environmental microbiota are thought to play a role in predisposed individual. Common symptoms include abdominal pain, diarrhea, fever, weight loss rectal bleeding. Diagnosis is made by clinical, laboratory, endoscopic, radiologic, histologic examinations. Nevertheless, about 15% patients do definitive diagnosis. Metabolomics measures metabolites biological sample (feces, serum, urine, tissue, air) thereby the potential clarify disease pathogenesis find new biomarkers, will then aid diagnosis, guide therapy, give prognosis.
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ژورنال
عنوان ژورنال: American journal of biomedical science & research
سال: 2022
ISSN: ['2642-1747']
DOI: https://doi.org/10.34297/ajbsr.2022.17.002356